Avano

This medication is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

• The recommended dose of Avano is once daily. Your physician will determine the appropriate dosage for you.
• Take Avano with or without food.

Warnings & Precautions

Consult your doctor or pharmacist before using Avano if you:

• Experience skin symptoms such as blistering, burning, or itching.
• Have kidney impairment.
• Have liver impairment.
• Have symptoms like pain, redness, or swelling between the genitals and anus.
• Have diabetic skin complications such as diabetic foot ulcers.
• Have a history of pancreatic disease.
• Are taking other antidiabetic medications.
• Have symptoms such as nausea, vomiting, hypothermia, bradycardia, respiratory difficulty, or muscle cramps.

Pregnancy & Breastfeeding

• If you are pregnant, may be pregnant, planning to become pregnant, or breastfeeding, consult your doctor or pharmacist before using this medicine.
• Avano is not recommended during the second and third trimesters of pregnancy, as its safety for the fetus has not been fully established.
• It is unknown whether linagliptin or empagliflozin are excreted into breast milk. Therefore, use of this medication during breastfeeding is not recommended.

Inform your doctor or pharmacist if you are currently using, have recently used, or may use any of the following medications:

• Insulin
• Sulfonylureas (e.g., glibenclamide, gliclazide)
• Anticonvulsants such as carbamazepine, phenobarbital, phenytoin
• Rifampin

Like all medicines, Avano may cause side effects, although not everyone gets them.
Side effect occurring in more than 10% of patients:

• Urinary tract infection

If You Take More Avano Than You Should
If you take more than the prescribed dose of Avano, immediately contact your doctor or go to the nearest hospital.

If You Forget to Take Avano
If you remember at least 12 hours before the next scheduled dose, take the missed dose immediately. Then continue with your regular dosing schedule.
If less than 12 hours remain before the next dose, skip the missed dose and take the next one at the usual time. Never take a double dose to make up for a missed one.

Do not use Avano if:

• You are allergic to linagliptin, empagliflozin, or any of the other ingredients in the formulation.
• You are on dialysis.

• Keep out of the sight and reach of children.
• Do not use after the expiry date stated on the packaging (Exp. Date:), which refers to the last day of that month.
• Store below 30°C, away from light and moisture.
• Keep in the original packaging until use.

This product is supplied in bottles containing 30 immediate-release tablets.